Top 10 Silymarin Suppliers, Manufacturers, Wholesalers, and Traders in San Marino

Established: 2005

Focus: Manufacturer & Wholesaler

San Marino Botanicals Ltd. is a household name in the local extract scene, and for good reason. With over 18 years of experience, this family-owned business has built a reputation for producing some of the purest silymarin in the region. What sets them apart? Their vertically integrated production process, which starts with sourcing organic milk thistle seeds from trusted farms in Italy and France. From there, they use a cold-press extraction method to preserve silymarin's active compounds, resulting in a product that's consistently high in potency—often testing at 80% silymarin content, well above industry averages.

Certifications are another strong suit here. San Marino Botanicals holds ISO 9001 and GMP certifications, and their facility is regularly audited by EU regulatory bodies. They cater to both small-scale buyers and large pharmaceutical companies, offering flexible bulk options (starting from 1kg up to 500kg per order) and even custom formulations, like silymarin capsules or liquid extracts. Customers rave about their responsive customer service and transparent sourcing practices—you can even request a batch-specific COA (Certificate of Analysis) to verify purity. If you're looking for a supplier that balances quality, reliability, and affordability, this is a solid starting point.

Established: 2010

Focus: Manufacturer & Exporter

Alpine Extracts Co. may be newer to the scene than some of its competitors, but it's quickly made a name for itself by specializing in pharmaceutical-grade silymarin. Located in the heart of San Marino's industrial zone, their state-of-the-art facility is equipped with cutting-edge extraction technology, including supercritical CO2 extraction, which ensures zero solvent residues and maximum purity. This makes their silymarin ideal for use in prescription medications and high-end supplements where precision is non-negotiable.

One of Alpine's standout offerings is their "UltraPure" silymarin line, which boasts a minimum of 90% silymarin content—perfect for clients in the pharmaceutical sector. They also offer a range of milk thistle extract derivatives, including silybin (the most active component of silymarin) and standardized extracts for cosmetic applications. What really impresses, though, is their commitment to sustainability. Alpine sources milk thistle seeds from organic, rain-fed farms in the Alpine region, reducing their carbon footprint, and their packaging is 100% recyclable. With a global client base spanning Europe, Asia, and North America, they're a great choice if you need a supplier with international shipping expertise and a focus on eco-friendly practices.

Established: 1998

Focus: Wholesaler & Trader

For those who prioritize variety and global sourcing, Mediterranean Silymarin Traders is a top pick. As one of the oldest extract traders in San Marino, they've built an extensive network of manufacturers across Europe, the Middle East, and South America, allowing them to offer a diverse range of silymarin products at competitive prices. Whether you need organic silymarin, conventional milk thistle extract, or even rare silymarin isolates, they likely have it in stock.

What makes Mediterranean Traders unique is their focus on small to medium-sized businesses. They understand that not every buyer needs a 1-ton order, so they offer flexible MOQs (minimum order quantities) starting at just 500g. This is a game-changer for startups or local supplement brands looking to test the market without committing to large volumes. They also provide personalized sourcing services—if you're after a specific type of silymarin (e.g., water-soluble or oil-soluble), their team will work with their global partners to track it down. With a reputation for on-time deliveries and a 24/7 customer support line, they're a reliable choice for buyers who value convenience and choice.

Established: 2015

Focus: Manufacturer & Researcher

GreenLeaf Biotech is where science meets nature. This innovative company prides itself on pushing the boundaries of silymarin extraction, investing heavily in R&D to develop new, more efficient methods. Their latest breakthrough? A patented ultrasonic extraction process that increases silymarin yield by 15% compared to traditional methods, while also reducing energy consumption. The result is a high-potency silymarin that's not only more effective but also more sustainable.

GreenLeaf specializes in silymarin for the nutraceutical and sports nutrition industries, offering products like microencapsulated silymarin (which improves bioavailability) and silymarin-infused protein powders. They also collaborate with universities and research institutions to study silymarin's potential benefits beyond liver health, including its antioxidant and anti-inflammatory properties. For buyers looking for cutting-edge, science-backed silymarin, GreenLeaf is hard to beat. Their facility is ISO 13485 certified (a standard for medical devices), and they offer comprehensive testing services, including HPLC and FTIR analysis, to ensure every batch meets specifications.

Established: 2008

Focus: Wholesaler & Private Label Supplier

If you're a brand looking to launch your own line of silymarin supplements, San Marino NutraIngredients is your one-stop shop. This wholesaler specializes in private label services, offering everything from silymarin powder to pre-made capsules and tablets, all ready to be branded with your logo. They work with a network of GMP-certified manufacturers to ensure quality, and their in-house lab tests every product for purity, potency, and contaminants.

What really stands out here is their attention to detail when it comes to formulation. Whether you want a standalone silymarin supplement or a blend (like silymarin + turmeric for joint health), their team of formulators will help you create a product that meets your target market's needs. They also offer packaging solutions, from eco-friendly bottles to blister packs, making the entire process seamless. MOQs are reasonable (starting at 1000 units for private label), and they provide support with regulatory compliance, including EU and FDA documentation. For entrepreneurs or established brands looking to expand their product line, San Marino NutraIngredients takes the hassle out of manufacturing.

Established: 2012

Focus: Manufacturer & Exporter

Blue Horizon Extracts has made a name for itself by focusing on organic and sustainably sourced silymarin. As a certified B Corp, they're committed to using business as a force for good, and that philosophy shines through in every aspect of their operation. They source milk thistle seeds from small-scale organic farms in Greece and Spain, paying farmers fair prices and ensuring ethical labor practices. Their extraction process uses only purified water and ethanol, avoiding harsh chemicals, and their facility runs on 100% renewable energy.

Their product line includes organic silymarin powder (certified by the EU Organic label), as well as organic milk thistle extract capsules and tinctures. They're a favorite among natural health brands and eco-conscious consumers, thanks to their transparent supply chain—you can even trace each batch back to the farm it came from via their online portal. Blue Horizon also offers bulk organic silymarin for cosmetic manufacturers, who use it in anti-aging serums and liver-supporting skincare lines. With a focus on sustainability without compromising on quality, they're a great choice for buyers who want to align their purchases with their values.

Established: 2001

Focus: Pharmaceutical Grade Supplier

When it comes to pharmaceutical-grade silymarin, Titan Pharma Ingredients is the gold standard in San Marino. This supplier caters exclusively to the pharmaceutical industry, providing high-purity silymarin that meets the strictest standards of the European Pharmacopoeia (Ph. Eur.) and the USP (United States Pharmacopeia). Their silymarin is used in prescription medications for liver disease, as well as in clinical trials for new therapeutic applications.

Titan's facility is a state-of-the-art cleanroom environment, complete with advanced testing equipment like HPLC-MS and GC-MS to detect even trace impurities. They offer silymarin in various grades, including USP Grade (minimum 70% silymarin) and Ph. Eur. Grade (minimum 85% silymarin), and can also produce custom isolates for specific research purposes. What sets them apart is their stringent quality control process—every batch undergoes over 20 tests before it's released, and they provide full documentation, including DMF (Drug Master File) support for clients submitting new drug applications. While their prices are higher than some general suppliers, the quality and reliability make them worth the investment for pharmaceutical companies.

Established: 2018

Focus: Budget-Friendly Wholesaler

For buyers on a tight budget, San Marino Extracts Wholesale offers high-quality silymarin at prices that won't break the bank. This newer entrant to the market has quickly gained traction by streamlining their operations—they work directly with a network of manufacturers in Eastern Europe and Asia, cutting out middlemen and passing the savings on to customers. Despite their low prices, they don't skimp on quality; all their silymarin is tested in an independent lab and comes with a COA.

They specialize in bulk orders (starting at 10kg), making them ideal for large-scale manufacturers or distributors. Their product range includes conventional silymarin powder (60-80% content), milk thistle extract tablets, and silymarin oil for cosmetic use. While they don't offer organic or pharmaceutical-grade options, their standard silymarin is more than sufficient for most supplement and cosmetic applications. Customers appreciate their straightforward ordering process and fast shipping—most EU orders arrive within 3-5 business days. If you need a reliable, cost-effective supplier for high-volume orders, San Marino Extracts Wholesale is worth considering.

Established: 2003

Focus: Traditional Extraction Specialist

Golden Seed Extracts takes a back-to-basics approach, using traditional extraction methods that have been refined over generations. While many suppliers rely on modern technology, Golden Seed swears by a cold maceration process, which they believe preserves more of silymarin's natural compounds. This results in a product with a slightly lower silymarin content (around 70%) but a richer profile of secondary phytochemicals, which some researchers believe work synergistically to enhance silymarin's benefits.

They source milk thistle seeds from a small cooperative of farmers in northern Italy, who have been growing the plant for over 50 years. The seeds are hand-harvested and sorted to ensure only the highest quality make it to extraction. Golden Seed offers small-batch silymarin powder, as well as artisanal milk thistle tinctures and teas, which are popular among herbalists and natural health practitioners. While their production capacity is smaller than some larger suppliers, they're a great choice for buyers who value tradition, craftsmanship, and a more holistic approach to extraction.

Established: 2014

Focus: International Trader & Logistics Expert

Rounding out our list is Global Silymarin Solutions, a San Marino-based trader that specializes in connecting buyers with the best silymarin suppliers worldwide. If you're looking for a specific type of silymarin (e.g., a rare isolate or a region-specific milk thistle extract), their team of sourcing experts will track it down for you. They work with manufacturers in over 20 countries, including hard-to-reach markets like India and Brazil, and have the logistics expertise to navigate complex import/export regulations.

What makes Global Silymarin Solutions stand out is their commitment to risk management. They conduct thorough due diligence on all their partner manufacturers, verifying certifications, testing facilities, and ethical practices before working with them. They also offer door-to-door shipping and customs clearance services, taking the stress out of international trade. Whether you're a pharmaceutical company needing a specific grade of silymarin or a supplement brand looking to source organic extract from a specific region, they'll handle the entire process from sourcing to delivery. With a focus on global reach and personalized service, they're a valuable partner for buyers with unique or specialized needs.