Top 10 Hyaluronic Acid Suppliers, Manufacturers, Wholesalers, and Traders in San Marino

Founded in 2005, SanMarin HA Solutions has grown from a small family-run operation to one of San Marino's most trusted names in hyaluronic acid. What started as a focus on skincare-grade hyaluronic acid has expanded to include pharmaceutical and supplement-grade products, making them a one-stop shop for businesses across industries. Walk into their facility in the heart of San Marino City, and you'll find a team of chemists and lab technicians obsessing over every batch—testing for purity, molecular weight, and consistency like it's their job (because it is).

Their claim to fame? A proprietary extraction process that preserves hyaluronic acid's natural structure, resulting in a product that absorbs faster in serums and delivers longer-lasting hydration in moisturizers. "We believe in transparency," says Maria Lombardi, their head of quality control. "Every client gets a detailed certificate of analysis, and we're happy to walk them through our sourcing—we work directly with sustainable fermentation facilities in Italy and France to ensure the raw materials meet our strict standards."

Key products include low-molecular-weight hyaluronic acid powder (perfect for serums that sink into skin quickly), high-molecular-weight gels for moisturizers, and oral supplement-grade capsules. They also offer custom formulations, so if you're dreaming up a hyaluronic acid-infused lip balm or a joint support powder, their R&D team is ready to collaborate. Minimum order quantities start at 5kg for bulk powder, but they're known for being flexible with small businesses—offering sample sizes so you can test before committing.

Why they stand out: Their dual focus on skincare and supplements means you can source all your hyaluronic acid needs from one supplier, cutting down on logistics headaches.

Nestled in the foothills of the Apennine Mountains, Alpine BioExtracts takes inspiration from San Marino's natural beauty—think crisp mountain air and pure spring water—and channels it into their hyaluronic acid production. Since 2010, they've specialized in organic-certified hyaluronic acid, a rarity in the industry, and their commitment to sustainability has earned them a loyal following among eco-conscious brands.

"We started because we noticed a gap," explains CEO Luca Moretti. "So many hyaluronic acid suppliers focus on synthetic production, but we wanted to create something that aligns with the 'clean beauty' movement. Our hyaluronic acid is derived from fermented plant sugars, not animal sources, and our facility runs on 100% renewable energy." It's a point of pride for them—you'll even find their sustainability report published on their website, detailing everything from water usage to carbon footprint.

Alpine's star product is their organic hyaluronic acid serum base , a pre-formulated blend that skincare brands can customize with essential oils or actives. It's become a favorite among indie beauty labels for its smooth texture and ability to enhance other ingredients like vitamin C. They also offer bulk organic hyaluronic acid powder for supplements, certified by the EU Organic Label and USDA Organic. For wholesalers, they provide large quantities (50kg+), with discounts for repeat orders and a dedicated account manager to handle logistics.

What sets them apart? Their customer service. "We once helped a small brand in Portugal reformulate their serum when they were struggling with viscosity," Luca recalls. "We didn't have to, but that's the Alpine way—we see ourselves as partners, not just suppliers." They also offer fast turnaround times, with most orders shipping within 3–5 business days, a bonus for businesses with tight production schedules.

Why they stand out: The only supplier in San Marino with EU and USDA organic certifications for hyaluronic acid, making them ideal for clean beauty and organic supplement lines.

Mediterranean Hyaluronics is all about precision. Founded by a team of former pharmaceutical researchers, this supplier specializes in pharmaceutical-grade hyaluronic acid , the kind used in medical devices, injectables, and high-end supplements. Their facility in Serravalle is ISO 9001 and GMP certified, with labs that look more like a hospital than a factory—think white coats, sterile equipment, and rigorous testing protocols.

"We don't cut corners," says Chief Scientific Officer Dr. Elena Rossi. "Our hyaluronic acid undergoes over 20 quality checks before it leaves our facility, including tests for endotoxins, heavy metals, and microbial contamination. For pharmaceutical clients, that's non-negotiable." It's this attention to detail that has made them a preferred supplier for European pharmaceutical companies and skincare brands that prioritize medical-grade ingredients.

Their product range includes low-viscosity hyaluronic acid for eye drops, high-purity powder for injectable fillers, and slow-release hyaluronic acid beads for sustained-release supplements. They also offer custom molecular weight options, which is crucial for clients developing specialized products—for example, a lower molecular weight for deeper skin penetration or a higher weight for joint lubrication. Minimum orders here are higher (starting at 20kg), but they make up for it with competitive pricing for bulk buyers and a technical support team available 24/7 to answer questions.

One unique offering? Their "Hyaluronic Acid 101" workshops. Several times a year, they invite clients to their facility for a day of training on formulation, quality control, and regulatory compliance. "We want our clients to feel confident in what they're buying," Dr. Rossi says. "Knowledge is part of the service."

Why they stand out: The go-to for pharmaceutical and medical-grade hyaluronic acid, with certifications that meet the strictest global standards.

For businesses that live and breathe bulk orders, Green Valley Wholesalers is the name to know. Since 2012, they've focused on one thing: providing high-quality hyaluronic acid at wholesale prices, with minimum orders starting at 100kg. They're not a manufacturer—instead, they partner with top producers in San Marino and Italy, curating a selection of hyaluronic acid powders, liquids, and pre-mixes to suit every budget and need.

"We work with over 50 suppliers globally, but our San Marino-sourced hyaluronic acid is our bestseller," says founder Marco Conti. "There's a reputation here for quality, and we pass that on to our clients at a fraction of the cost. Whether you need 100kg for a large-scale skincare line or 500kg for a supplement brand, we can deliver."

Green Valley's strength is variety. They stock everything from cosmetic-grade hyaluronic acid (ideal for moisturizers and serums) to food-grade powder for beverages and gummies. They also offer private labeling services—so if you want to slap your brand name on a hyaluronic acid serum base, they'll handle the packaging and formulation. Their website features a handy "request a quote" tool, where you can input your quantity and product type, and get a price within 24 hours—no endless back-and-forth emails required.

What makes them popular? Reliability. "We once had a client in Germany who needed an emergency order after their regular supplier fell through," Marco laughs. "We shipped 200kg overnight—cost us a pretty penny, but they've been with us ever since." They also offer flexible payment terms for long-term clients, including net-30 options, which is a lifesaver for businesses managing cash flow.

Why they stand out: The best choice for bulk buyers, with unbeatable wholesale pricing and a massive inventory of hyaluronic acid types.

Serene Skin Ingredients is all about the beauty side of hyaluronic acid. If you're a skincare brand looking to create that viral hyaluronic acid serum or a moisturizer that gets rave reviews, this supplier has you covered. Founded by a team of former beauty industry insiders, they understand the unique needs of cosmetic formulators—like texture, absorption, and that "luxury feel" customers love.

"We started because we were frustrated with suppliers who didn't 'get' skincare," says co-founder Sofia Bianchi. "Hyaluronic acid isn't just an ingredient; it's part of the user experience. Does it feel sticky? Does it layer well under makeup? Those are the questions we ask." Their lab in Domagnano is equipped with sensory testing stations, where they evaluate how their hyaluronic acid performs in different formulations—from lightweight gels to rich creams.

Serene's claim to fame is their "SilkTouch" hyaluronic acid, a low-molecular-weight powder that dissolves instantly in water, leaving zero stickiness. It's a hit with brands creating serums for oily or combination skin, as it hydrates without heaviness. They also offer a "Plump & Glow" blend, which combines hyaluronic acid with niacinamide and peptides for an all-in-one anti-aging boost. For small businesses, they offer small minimum orders (just 1kg) and even sample sachets so you can test the texture before buying in bulk.

What really sets them apart is their formulation support. "We don't just sell you powder and send you on your way," Sofia says. "Our team will help you tweak your recipe—maybe adjust the pH or suggest a thickener—to make sure your product shines." They also stay on top of trends, recently launching a "Clean Beauty Collection" with hyaluronic acid derived from fermented coconut sugar, perfect for brands targeting the Gen Z market.

Why they stand out: Skincare-specific expertise and sensory testing make them ideal for brands focused on consumer experience.

NutraHA Traders bridges the gap between hyaluronic acid and the supplement industry. If you're creating capsules, powders, or gummies that promote joint health or skin hydration from the inside out, this trader has the connections and expertise to source the right product. They work with a network of San Marino-based manufacturers to offer a range of supplement-grade hyaluronic acid, from quick-dissolve powders to slow-release beads.

"Supplements have different requirements than skincare," explains trader Giovanni Rizzo. "You need stability, bioavailability, and often, certifications like Kosher or Halal. We specialize in finding hyaluronic acid that checks all those boxes." Their most popular product is their hyaluronic acid supplement powder , which is micronized for better absorption—meaning more of the ingredient actually gets into the bloodstream, where it can support joints and skin.

NutraHA Traders doesn't just sell ingredients; they also offer regulatory support. "We know navigating the EU's Novel Food regulations or the FDA's supplement guidelines can be overwhelming," Giovanni says. "Our team will help you gather the necessary documentation, like safety data sheets and clinical studies, to get your product to market faster." They also keep a close eye on research, recently adding a hyaluronic acid and collagen blend based on studies showing the two ingredients work better together for joint health.

Minimum orders here start at 5kg, but they're flexible for repeat clients, offering volume discounts and priority shipping. They also partner with contract manufacturers in San Marino, so if you need help turning your hyaluronic acid powder into finished capsules, they can connect you with a facility that handles everything from encapsulation to labeling.

Why they stand out: Specialized in supplement-grade hyaluronic acid with a focus on bioavailability and regulatory support.

BioPure San Marino is for the businesses that refuse to compromise on purity. Founded in 2018 by a group of biochemists, this manufacturer prides itself on producing hyaluronic acid with 99.9% purity—a level that's hard to find elsewhere. Their facility uses advanced filtration technology to remove even trace impurities, making their product ideal for sensitive applications like baby skincare or medical devices.

"We started with a simple mission: create the purest hyaluronic acid on the market," says founder Dr. Matteo Ferri. "We noticed that many suppliers cut corners, adding fillers or diluting their product to save money. We never do that. What you see on the label is exactly what you get." Their commitment to purity has earned them partnerships with luxury skincare brands and pediatric product lines, who value their transparency and rigorous testing.

BioPure's product line includes pharmaceutical-grade hyaluronic acid for injectables, cosmetic-grade powder for skincare, and even ultra-pure liquid hyaluronic acid for eye drops. They also offer custom purification services—so if you need a specific molecular weight or impurity profile, their team can tailor the process to your needs. While their prices are higher than some competitors, clients say the quality is worth it. "You're paying for peace of mind," one customer review reads. "No surprises in the lab results, no failed batch tests—just consistent, pure product."

What's unique about BioPure? Their "Purity Promise." If a batch doesn't meet their 99.9% purity standard, they'll ｒｅｐｌａｃｅ it for free and provide a full refund. "It's our way of standing behind our product," Dr. Ferri says. "We've only had to do it twice in five years, but it shows we mean business."

Why they stand out: Unmatched purity levels (99.9%) make them the top choice for sensitive applications like baby products and medical devices.

Global HA Logistics is the trader with a global reach. While based in San Marino, they specialize in connecting international buyers with San Marino's best hyaluronic acid manufacturers, handling everything from sourcing to shipping. If you're a business in Canada, Australia, or Brazil looking to import hyaluronic acid from San Marino, this is your one-stop logistics partner.

"We speak the language of both suppliers and buyers," says founder Alessandra Toni. "A manufacturer in San Marino might not understand the import regulations in Brazil, and a buyer in Australia might not know which supplier offers the best cosmetic-grade hyaluronic acid. We bridge that gap." Their team includes experts in international trade, customs, and logistics, ensuring your order clears customs smoothly and arrives on time.

Global HA Logistics works with all the top manufacturers on this list, so they can source any type of hyaluronic acid—organic, pharmaceutical-grade, bulk wholesale, you name it. They also offer consolidated shipping, which is a game-changer for small businesses. "Instead of paying for a full container, you can share space with other buyers, reducing costs," Alessandra explains. "We recently helped a startup in Canada save 30% on shipping by consolidating their order with three other brands."

What makes them indispensable? Their knowledge of global regulations. "Each country has its own rules," Alessandra says. "For example, the EU requires certain certifications that the US doesn't, and Australia has strict quarantine laws for imported ingredients. We make sure your order meets all those requirements, so you don't get stuck with a shipment held at customs." They also offer insurance options, so you're covered if anything goes wrong during transit.

Why they stand out: Ideal for international buyers, with expertise in global shipping, customs, and regulations.

PureScience Manufacturing is the tech-savvy manufacturer using cutting-edge fermentation technology to produce hyaluronic acid. Founded in 2017, they've quickly made a name for themselves with their innovative approach, which uses genetically modified yeast to produce hyaluronic acid with precise molecular weights—no animal products, no harsh chemicals.

"Traditional fermentation uses bacteria, which can be unpredictable," explains lead scientist Dr. Carlo Neri. "Our yeast-based process gives us control. Want a hyaluronic acid with a molecular weight of 500 kDa for deep skin hydration? We can produce it consistently, batch after batch." This precision has made them a favorite among brands creating specialized products, like targeted anti-aging serums or high-performance supplements.

PureScience's product line includes "Custom Molecular Weight" hyaluronic acid, where clients can specify exactly the size they need, and "EcoHA," their sustainable line produced with 70% less water than traditional methods. They also offer fast prototyping—if you need a small batch (as little as 500g) for testing, they can have it ready in under a week. "Speed is key in this industry," Dr. Neri says. "Brands need to iterate quickly, and we help them do that."

While their technology is advanced, their pricing is surprisingly competitive, thanks to efficient production methods. They also offer transparency into their process, with virtual tours of their lab available upon request. "We want clients to see how their product is made," Dr. Neri adds. "Trust is everything."

Why they stand out: Innovative yeast-based fermentation for precise molecular weights, perfect for specialized formulations.

Harmony Health Ingredients rounds out our list as the supplier focused on holistic health. They specialize in hyaluronic acid blends for wellness products, combining it with other natural ingredients like collagen, vitamins, and herbal extracts. If you're creating a "beauty from within" supplement or a skincare line that marries science and nature, this is your match.

"Hyaluronic acid works best when paired with other nutrients," says founder Clara Vitali. "For example, vitamin C helps boost collagen production, which complements hyaluronic acid's hydrating effects. We've spent years researching these synergies to create ready-to-use blends." Their most popular blend is "Glow+," which combines hyaluronic acid with collagen peptides, vitamin E, and astaxanthin (a powerful antioxidant) for a comprehensive skin support supplement.

Harmony Health Ingredients offers both pre-formulated blends and custom options. If you have a specific ingredient you want to pair with hyaluronic acid—say, turmeric for anti-inflammatory benefits or biotin for hair health—their R&D team will develop a blend tailored to your goals. They also prioritize clean, non-GMO ingredients, with all blends tested for allergens and contaminants. Minimum orders start at 2kg for blends, and they offer free samples so you can test the flavor and texture (important for supplements that need to taste good!).

What makes them unique? Their focus on education. "We don't just sell blends; we teach you how to market them," Clara says. "We provide research summaries, marketing copy, and even social media content ideas to help your product stand out." It's a boon for small brands that might not have a dedicated marketing team.

Why they stand out: Expertise in hyaluronic acid blends with other wellness ingredients, plus marketing support for brands.